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Alzheimer's Disease/Dementia
Brain Tumors
Brain and spinal cord tumors remain a significant problem but new
methods of treatment offer improved survival and quality of life
in many cases. The neuro-oncology program and clinic is a multidisciplinary
effort including faculty from neurology, radiation oncology, neurosurgery,
medical oncology and neuroradiology. It is an integral part of
the Wertz Clinical Cancer Center.
Charcot-Marie-Tooth Disease
Charcot-Marie-Tooth disease (CMT), named for the three doctors
who described the condition in the late 1800s, is one of the most
common inherited neurological conditions. About one in 2,500 people
have CMT. CMT first affects the lower legs and feet leading to
weakness, numbness, and sometimes changes in the shape of the foot.
As the condition progresses, weakness and numbness can also occur
in the hands and forearms. CMT does not affect a person's intelligence
and is not associated with a shortened life span.
Epilepsy
The Comprehensive Epilepsy Program is dedicated to the care of
people with epilepsy. The program provides state-of-the-art medical
and surgical treatment for adults and children with epilepsy. We
offer a full complement of advanced diagnostic tests to establish
seizure classification, to assess response to medical therapy and
to evaluate patients for epilepsy surgery.
Headaches
Head Injury
Head and spinal cord injuries are still a major cause of death
and disability. They often affect the young and adults in their
most productive years. Both acute and chronic care of victims of
neurotrauma are supervised by multidisciplinary teams of neurosurgeons,
neurologists, physical medicine specialists and therapists. The
neurotrauma clinic has a full-time nurse clinician and works with
physical medicine and rehabilitation. It is directly related to
the multidisciplinary in-patient program, and includes its patients
in on-going research protocols.
Movement Disorders
A full range of treatment for movement disorders is offered at
WSU, including the latest medications for Parkinson's disease;
evaluation and referral for Parkinson's surgery; medical tremor
therapy and evaluation for surgical tremor therapy; botulinum toxin
(Botox) therapy for torticollis and other dystonias; evaluation,
diagnosis and management of hereditary movement disorders, including
Huntington's, Wilson's and spinocerebellar ataxias; and evaluation,
diagnosis and treatment of Farr's disease and other calcifications
of the basal ganglia.
Multiple Sclerosis
Wayne State University has a very active comprehensive center for
the evaluation and treatment of those with multiple sclerosis and
other demyelinating diseases of the central nervous system. In
addition to neurologists, the clinic is staffed by nurses, physical
therapists, psychologists and physiatrists. WSU is also very active
in clinical trials of new treatments for MS as well as in basic
research relevant to this chronic illness.
Myasthenia Gravis
Myasthenia gravis is a disorder caused by the immune system developing
immunity to a critical protein, the acetylcholine receptor, on
muscles needed to detect signals from motor nerves. The immune
reaction prevents the receptor from responding to the neurotransmitter
acetylcholine and leads to destruction of the neuromuscular junction,
the site of nerve contact with the muscle. In addition to having
a clinic for the evaluation and treatment of patients with myasthenia
gravis, Wayne State University neurologists have had ongoing research
on this subject for many years.
Nerve and Muscle Disease
Neurogenetics
The neurogenetics clinic at Wayne State University offers comprehensive
diagnostic and care services for those who have or who are suspected
of having a genetic disorder affecting the nervous system or muscles.
Examples of such disorders include Huntington disease, spinocerebellar
ataxias, muscular dystrophies, mitochondrial disorders, leukodystrophies,
hereditary spastic paraplegia, Charcot-Marie-Tooth disease, neurofibromatosis,
tuberous sclerosis, Friedreich's ataxia and some types of Alzheimer's
disease and amyotrophic lateral sclerosis. Testing and counseling
are available for those who are at risk for, but do not yet manifest
symptoms of a disease, such as Huntington disease. The decision
to undergo this testing should be made only after careful consideration
for one's own need to know this information, along with concerns
for one's family, occupation and financial planning. Prenatal testing
for some disorders may be possible once it is established through
molecular testing that a couple is at risk for passing a genetic
condition to a child.
Pediatric Neurology
Pelizaeus-Merzbacher Disease
Pelizaeus-Merzbacher disease is a rare disorder that usually affects
only males. It results from genetic alteration or mutation of the
gene for proteolipid protein, the major protein in the myelin of
the brain and spinal cord.
Stroke
Stroke is the third leading cause of death in the United States
and is a leading cause of disability. About 500,000 people in the
U.S. have a stroke each year and 150,000 die from stroke. The Wayne
State University Stroke Program is providing metro Detroit not
only with top-notch care and research, but an ambitious community
outreach program to prevent strokes from ever occurring.
Positron Emission Tomography Center
Since January 1994, the PET Center at Children's Hospital of Michigan
has provided a variety of scans, both for clinical care and research,
to patients of all ages from Michigan and abroad. Wayne State
University and Children's Hospital of Michigan share this substantial
resource with the community to detect seizure epileptic foci; to
determine serotonin synthesis capacity in autism and tuberous sclerosis;
to evaluate heart disorders and cardiac viability; and to identify
malignant diseases or tumors and to monitor their therapy.
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